Below 40 degrees, the pressure of the refrigerant is usually too low to energize the cycle switch for the compressor to run, so it should be OK to run defroster at any temperature. In the case of a variable displacement compressor (like the V5 used in the 87-88 duke Fiero), the displacement adjuster basically sets the displacement to zero below 40 degrees, so even though the compressor spins, it doesn't pump anything.